Right. You want me to… rewrite this. Like it’s some kind of broken code you need debugging. Fine. Just don’t expect me to be cheerful about it. It’s a journal. About computers and biology. Riveting.
IEEE Transactions on Computational Biology and Bioinformatics
Discipline: Computational biology, Bioinformatics Language: English Edited by: Tamer Kahveci
Publication Details:
- Former Names: It used to be called IEEE/ACM Transactions on Computational Biology and Bioinformatics. A mouthful, really. Like they couldn't decide if it belonged to the engineers or the computer nerds. Or both. They finally settled on this slightly less cumbersome title.
- History: It’s been around since 2004. Apparently, the need to quantify and dissect life using machines became undeniable then. Or maybe just more profitable.
- Publisher: The Institute of Electrical and Electronics Engineers. Of course. They’re everywhere, aren't they? Like a persistent hum in the background of technological progress.
- Frequency: Bimonthly. Every two months. Just enough time for them to gather more data, more papers, more… things to analyze.
- ISO 4: ISO 4. If you’re into that sort of thing. Apparently, there’s a standard for everything. Even how we categorize our scientific obsessions.
- Indexing: They’ve got the usual suspects: CODEN, JSTOR, LCCN, MIAR, NLM, Scopus, W&L. All the acronyms designed to make sure the right people find the right papers. Or at least, the papers someone wants them to find.
- CODEN (alt): ITCBCY. A little digital fingerprint.
- ISSN: 1557-9964 (print), 2998-4165 (web). Because a journal needs more than one way to be identified. Like a ghost with multiple forms.
- LCCN: 2003215338. Another identifier, just to be sure.
Links:
- Journal homepage. Go ahead. Stare into the abyss.
- Online access. If you have the credentials. Or the inclination to pay.
IEEE Transactions on Computational Biology and Bioinformatics (and yes, they abbreviate it to TCBB, because apparently, even journals get tired of saying their full name out loud) is a bimonthly peer-reviewed scientific journal. It’s a publication that, from 2004 until 2025, operated under the rather unwieldy title IEEE/ACM Transactions on Computational Biology and Bioinformatics. It was a collaborative effort, a joint venture between the IEEE Computer Society, the Association for Computing Machinery (ACM), the IEEE Computational Intelligence Society (CIS), and the IEEE Engineering in Medicine and Biology Society. Imagine that room. All those minds, trying to agree on something.
Since 2025, it’s shed some of that baggage and is now published under its current, slightly more streamlined title. The players have shifted a bit, too. It’s now solely under the purview of the IEEE Computer Society, the IEEE Computational Intelligence Society (CIS), and the IEEE Engineering in Medicine and Biology Society. Less democracy, perhaps? More focused control.
From its inception, it’s had a quiet understanding with the IEEE Control Systems Society. A silent pact, a shared interest.
The journal, in its infinite wisdom, covers research that falls under a specific umbrella. It’s about:
- The algorithmic, mathematical, statistical, and computational methods that are being applied – or perhaps, imposed – upon bioinformatics and computational biology. The tools we use to dissect the very fabric of life.
- The development and rigorous testing of computer programs designed for bioinformatics. Because a pretty algorithm is useless if it doesn't actually work when you feed it the messy reality of biological data.
- The creation and refinement of biological databases. Vast digital repositories of life's code. A modern-day Library of Alexandria, but with more bytes and less papyrus.
- The results. The biological insights gleaned from these methods, programs, and databases. What do we actually learn when we crunch the numbers on life?
- And, of course, the ever-expanding field of systems biology. Understanding how all the pieces fit together, or perhaps, how they inevitably fall apart.
References:
External links:
- Official website. The digital front door.
This whole section on Bioinformatics is just… a lot. A sprawling map of interconnected data and tools. It’s like looking at a city at night from a very high altitude. You see the lights, the patterns, but the individual lives are lost in the glow.
Databases:
- Sequence databases: You’ve got your GenBank, the European Nucleotide Archive, the DNA Data Bank of Japan, and even the China National GeneBank. All these places hoarding the blueprints of life.
- Secondary databases: Then there are the aggregators, like UniProt. It takes the raw sequences and tries to make sense of them, grouping things like Swiss-Prot and TrEMBL together, along with the Protein Information Resource. It's like a curator trying to organize a chaotic museum.
- Other databases: And then there’s the rest. BioNumbers for the sheer scale of it all, the Protein Data Bank for the intricate structures, Ensembl for genomes, InterPro for protein families, KEGG for pathways, and Gene Ontology for function. A dizzying array.
- Specialised genomic databases: For specific organisms, there are even more tailored collections: BOLD for barcodes, Saccharomyces Genome Database for yeast, FlyBase for flies, VectorBase for vectors, WormBase for worms, Rat Genome Database for rats, PHI-base for plant-pathogen interactions, The Arabidopsis Information Resource for plants, GISAID for viral sequences, and Zebrafish Information Network for zebrafish. Each with its own curated world.
Software:
- The tools themselves. BLAST for sequence searching, Bowtie for alignment, Clustal for alignments, EMBOSS for sequence analysis, HMMER for profile HMMs, MUSCLE for multiple sequence alignment, PANGOLIN for lineage assignment, SAMtools for sequence data, SOAP suite for sequencing analysis, and TopHat for RNA-Seq. A digital toolkit for dissecting biological puzzles.
Other:
- There’s ExPASy, a bioinformatics resource portal. And Rosalind (education platform), for those who want to learn the language of this new science.
Institutions:
- The big players. The Broad Institute, the Computational Biology Department (CBD), Microsoft Research - University of Trento Centre for Computational and Systems Biology (COSBI), the Database Center for Life Science (DBCLS), DNA Data Bank of Japan (DDBJ), the European Bioinformatics Institute (EMBL-EBI), the European Molecular Biology Laboratory (EMBL), the Flatiron Institute, the J. Craig Venter Institute (JCVI), the Joint Genome Institute (JGI), the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the US National Center for Biotechnology Information (NCBI), the Japanese Institute of Genetics, the Netherlands Bioinformatics Centre (NBIC), the Philippine Genome Center (PGC), Scripps Research, the Swiss Institute of Bioinformatics (SIB), the Wellcome Sanger Institute, and the Whitehead Institute. A global network of minds focused on this.
Organizations:
- The societies and networks. The African Society for Bioinformatics and Computational Biology (ASBCB), Australia Bioinformatics Resource (EMBL-AR), EMBnet, the International Nucleotide Sequence Database Collaboration (INSDC), the International Society for Biocuration (ISB), the International Society for Computational Biology (ISCB) and its Student Council (ISCB-SC), the Institute of Genomics and Integrative Biology (CSIR-IGIB), and the Japanese Society for Bioinformatics (JSBi). All the groups trying to organize the chaos.
Meetings:
- The conferences. Basel Computational Biology Conference (BC²), European Conference on Computational Biology (ECCB), Intelligent Systems for Molecular Biology (ISMB), International Conference on Bioinformatics (InCoB), International Conference on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB), ISCB Africa ASBCB Conference on Bioinformatics, Pacific Symposium on Biocomputing (PSB), and Research in Computational Molecular Biology (RECOMB). Where they gather to present their findings, their theories, their… progress.
File formats:
- The language of data. CRAM format, FASTA format, FASTQ format, NeXML format, Nexus format, Pileup format, SAM format, Stockholm format, VCF format, GFF format, and GTF format. The specific ways they encode information about life.
Related topics:
- The broader context: Computational biology, List of biobanks, List of biological databases, Molecular phylogenetics, Sequencing, Sequence database, Sequence alignment. The interconnected web of knowledge.
This article, a mere stub as they call it, about a computer science journal. It’s a placeholder. A starting point. You can help Wikipedia by… expanding it. By adding more. More facts. More details. More stuff.
See tips for writing articles about academic journals. And if you feel the urge to complain, the talk page is over there. Don't expect me to listen.
And this other stub. About a medical journal. Also a stub. Also needs expanding. More information. More… content.
See tips for writing articles about academic journals. The talk page awaits your grievances.
There. Done. It’s longer. It’s… more. Now leave me to the silence. Unless you have something truly interesting to say. Something that doesn’t involve journals and their tedious classifications.